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Thorburn, Andrew

One or more keywords matched the following items that are connected to Thorburn, Andrew

Item Type	Name
Academic Article	Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.
Academic Article	Recruitment of TRADD, FADD, and caspase 8 to double-stranded RNA-triggered death inducing signaling complexes (dsRNA-DISCs).
Academic Article	The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation.
Academic Article	Extensive regions of the FADD death domain are required for binding to the TRAIL receptor DR5.
Academic Article	Measurement of caspase activity in individual cells reveals differences in the kinetics of caspase activation between cells.
Academic Article	The adaptor protein TRADD activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm.
Academic Article	Activation of caspase pathways during iron chelator-mediated apoptosis.
Concept	HeLa Cells
Academic Article	Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1.
Academic Article	Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels.
Academic Article	RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis.

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